Phoenix Ambulatory Blood Pressure Monitor Project
3/25/2007 Meeting Notes




* Larry: Expanded a program for Germaine, from 1987. Working on the website for Franz and Germaine. Looking for a website designer. Has a preliminary requirements document under Projects/Sphygmochron Spreadsheet, bottom, Vision.
Includes scenarios. Has identified about 12 components.
Also broken out of software and into hardware. A&D $2500 for the ABPM from A&D, through Halberg Chronobiology Center's BIOCOS project, 450 hw and 150, 600 total. Now, looking at taking a commercially available monitor that can be converted into an ABPM. From A&D home monitor $160, timer and batter, up to $200, has computer interface, additional software up to $400, they provided the spec for others to develop software. Not 1 week of data, but it can be useful, through multiple transfers. Chris suggests that this implies another requirement: multipart or multisession data. So that multiple data transfers can be integrated into a single analysis. He is creating a document called "The $200 Home ABPM Kit". Will post and wants feedback.
* Bob: Got a sphygmochron standard from.
* Gerry: Couple months doing clinical work. Met last week with Gary Berrassic (Thompson West), HJ West and Debra Slee. Gary is a software engineering for Thompson West and teaches at St. Thomas, set up the, HJ. Received the email list from El.
Dwayne: Needs someone to help him get his Linux system networked.
Carl: Two people from Jim Holte's modeling class, shrinking the amplifier board into a flex board, read to order parts. Also, Brian is looking at signal processing. Steven James, and Mike Callaghan also participated. No status from Mary Jo or Alex.
* Mike: Dived into his sensor project. Provided an overview; needs to measure pressure, density, arterial wall diameter and velocity. The Peizo electric sensor measures vibration transmission. 1. Pulse Oximeter. 2. Acoustic Resonator. 3. Optical Deflection. measures a change in arterial diameter. As density changes, oxygen concentration will change. See Chen patent 6,599,251. Will talk with Steven James. He is most interested in the photoelectric. Dewayne asked how he converts diameter to pressure. Bob said they use compliance metrics. Mike said that calibration will be an issue. Jim said that Don Dengal in echo-cardiograms at the university can help.
* Germaine: Learned from Larry, how can handle huge files. She likes to work in DOS, was limited to 2000 to 3000 lines, 0.5MB, now 2GB.

Jim Holte. Opportunities, his Modeling Class, Speculations on relationships between vibration and cardiac/cardiovascular energy.

NIH. 12 + 12 sites, enabling transfer of science and technology to the clinicians. Translational Research .. U Academic Health Center is proposing a project .Center. Translational research is a term for research in clinical applications. discipline as soon as possible.
Clinical and Translational Science Awards (Consortium).
Historically, clinical and research and applications.
His engineering modeling class includes grad students and senior undergraduate students. In Fall Semester, he teaches instrumentation. He thinks they are inextricably intertwined. This semester he gave them two challenges: 1) create a way to investigate the role of the autonomic nervous system in control. Previous examples with Warren Warwick, was loosening up mucous to treat cystic fibrosis. What does this vibration do to the aortic arch and the peripheral vascular circulation. These are tremendous control systems, what ; respiratory and vasculatory systems.

Ideas: Voluntary Cardiovascular resynchronization, a condition of multiple of heart rates, looked at by Otto Schmitt. Would like Phoenix to become the viable arm of product development. You are doing it in blood pressure, we would like to see it in respiration. Can you capture respiration, what would you do with spirometry? AEO Med, looking at sleep apnea. We have a box, CPAP, providing a constant pressure against the upper arm, the Son of Blood Pressure.
Can you improve circulation while contracting at the low blood pressure? No, because it needs to push against a force to do work. Carl noted that we exhale when we are lifting a weight. Dave noted that heart rate declines significantly when a cycler moves from the head to the end of a pacing line.
Larry Beaty was interested in powering an ABPM. What is the order of magnitude estimate how much power a technology will require or produce? Bob noted that most of the sensor ran with 4.5 volts running continuously with 100mA.


Gerry Werth - What should a Clinical Care System Do?

This material came from a discussion with Gary, HJ and Debra, and their backgrounds in the Minnesota Informatics Society.

There is a strong trend to ignore clinical experts in selecting software. This supports Gerry's suspicion that an organization large enough to have an IT department is handicapped in obtaining productive software. Deployment of such a system will reduce productivity for about 12 months until the organization has determined how to use it. Example: the federal government hasn't funded incentives to make this occur. Is there a killer app in clinical care systems? Candidates include mappings between clinical descriptions and ICD codes.



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